Join us as we dive into the microscopic realm with our webinar on bacterial nucleotide second messengers! In this session, we unveil the mysteries behind Streptomyces' response to osmotic stress, shedding light on alternative sigma factors, two-component systems, and the role of c-di-AMP in osmoregulation. Explore the intricate world of c-di-GMP signaling networks, dissecting the criteria for local signaling in Escherichia coli and Pseudomonas. Unravel the unique role of c-di-AMP in Bacillus subtilis, acting as both a survival essential and a potential toxin, impacting potassium homeostasis and amino acid regulation. Lastly, journey into the diverse functions of (p)ppGpp alarmones in bacterial stress responses, unveiling their overlap with the transcriptional regulator Spx in Bacillus subtilis. |
